Vitamin C kills drug-resistant TB(MDR-TB) in lab tests

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This is a great and surprise discovery that leads to a new hope .
Reseachers at New York’s Yeshiva University have accidentally discovered that Vitamin C can kill multi-drug resistant TB bacteria in a laboratory experiment.

Multi-drug-resistant tuberculosis (MDR-TB) is defined as tuberculosis that is resistant to at least isoniazid (INH) and rifampicin (RMP), the two most powerful first-line treatment anti-TB drugs. Isolates that are multiply resistant to any other combination of anti-TB drugs

An estimated 650,000 people worldwide have multidrug-resistant TB.

But this is an experimental result .Studies are now needed to see if a treatment that works using the same action as vitamin C would be useful as a TB drug in humans.

According to the lead investigator Dr William Jacobs, professor of microbiology and immunology at Albert Einstein College of Medicine at Yeshiva University, said: “We have only been able to demonstrate this in a test tube, and we don’t know if it will work in humans and in animals.

“This would be a great study to consider because we have strains of tuberculosis that we don’t have drugs for, and I know that in the laboratory we can kill those strains with vitamin C.”

“It also helps that we know vitamin C is inexpensive, widely available and very safe to use. At the very least, this work shows us a new mechanism that we can exploit to attack TB.”

BBC Reported

The term “totally drug resistant” has not been clearly defined for tuberculosis. While the concept of “total drug resistance” is easily understood in general terms, in practice, in vitro drug susceptibility testing (DST) is technically challenging and limitations on the use of results remain

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